A second hacked email has surfaced that appears to show Democratic consultant Donna Brazile sharing a debate question with Hillary Clinton’s campaign in advance of a March primary debate.

Ms. Brazile—then a CNN contributor and Democratic Party official—warned one day before a March primary debate hosted by CNN in Flint, Mich., that a question would come “from a woman with a rash.”

“Her family has lead poison and she will ask what, if anything, will Hillary do as president to help the [people] of Flint,” Ms. Brazile wrote in an email addressed to Clinton campaign communications director Jennifer Palmieri and campaign chairman John Podesta.

The email was stolen from Mr. Podesta’s inbox and posted by the website WikiLeaks. Ms. Brazile currently is the interim chair of the Democratic National Committee.

The Clinton campaign has declined to confirm or deny the authenticity of the stolen emails and has pointed to possible links to the Russian government as evidence of foreign tampering in the election.

The question referred to the drinking water crisis in Flint, Mich., where lead had contaminated the city’s water supply. CNN held a Democratic debate in the city in March between Mrs. Clinton and her rival for the Democratic nomination Bernie Sanders at the height of public attention on the drinking water crisis.

It is the second instance where Ms. Brazile appeared to have access to a question from a CNN-hosted event, where she also served as a contributor until earlier this year when she severed ties with the network. A previously leaked email showed that she had shared the exact wording of a question that would be asked one day later at a CNN town hall event.

Asked to comment on the latest email, Ms. Brazile on Monday referred to statement she issued earlier in the month where she said: “As a longtime political activist with deep ties to our party, I supported all of our candidates for president. I often shared my thoughts with each and every campaign, and any suggestions that indicate otherwise are simply untrue. As it pertains to the CNN Debates, I never had access to questions and would never have shared them with the candidates if I did.”

CNN spokesperson Lauren Pratapas said that Ms. Brazile resigned from the network on Oct. 14 and she had previously suspended her role with CNN after becoming DNC chairwoman this summer.

“CNN never gave Brazile access to any questions, prep material, attendee list, background information or meetings in advance of a town hall or debate. We are completely uncomfortable with what we have learned about her interactions with the Clinton campaign while she was a CNN contributor,” Ms. Pratapas said.

By Byron Tau